Invited Book Chapters
Chen, L. C., Lloyd, W. R., Chang, C. W., Sud, D., and Mycek, M. A., “Fluorescence lifetime imaging microscopy for quantitative biological imaging”, Methods Cell Biol., 2013, 114, 457-488 (PDF)
Chang, C. W., Mycek, M. A., “Quantitative molecular imaging in living cells via FLIM”, Reviews in Fluorescence 2010, 2012, 173-198 (PDF)
Chang, C. W., Sud, D., Mycek, M. A., “Fluorescence lifetime imaging microscopy”, Methods Cell Biol., 2007, 81, 495-524 (PDF)
Invited Book Chapters
Chen, L. C., Lloyd, W. R., Chang, C. W., Sud, D., and Mycek, M. A., “Fluorescence lifetime imaging microscopy for quantitative biological imaging”, Methods Cell Biol., 2013, 114, 457-488 (PDF)
Chang, C. W., Mycek, M. A., “Quantitative molecular imaging in living cells via FLIM”, Reviews in Fluorescence 2010, 2012, 173-198 (PDF)
Chang, C. W., Sud, D., Mycek, M. A., “Fluorescence lifetime imaging microscopy”, Methods Cell Biol., 2007, 81, 495-524 (PDF)
Peer-Revewed Journal Articles
Chang, C. W., Kumar, S., “Vinculin tension distributions of individual stress fibers within cell-matrix adhesions”, Journal of Cell Science, 2013, 126(14), 3021-3030 (PDF) (JCS Highlight) (F1000 Review).
Paulsen, M. T., Veloso, A., Prasad, J., Bedi, K., Ljungman, E. A., Tsan, Y. C., Chang, C. W., Tarrier, B., Washburn, J. G., Lyons, R., Robinson, D. R., Kumar-Sinha, C., Wilson, T. E., Ljungman, M., “Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response”, Proceedings of the National Academy of Sciences, 2013, 110(6), 2240-2245 (PDF)
Chang, C. W., Mycek, M. A., “Total variation versus wavelet-based methods for image denoising in fluorescence lifetime imaging microscopy”, Journal of Biophotonics, 2012, 5(5-6), 449-57 (PDF)
Chang, C. W., Mycek, M. A., “Enhancing precision in time-domain fluorescence lifetime imaging”, Journal of Biomedical Optics, 2010, 15(5), 056013 (PDF)
Lloyd, W. R., Wilson, R. H., Chang, C. W., Gillispie, G. D., Mycek, M. A., “Instrumentation to rapidly acquire fluorescence wavelength-time matrices of biological tissues”, Biomedical Optics Express, 2010, 1(2), 574–586 (PDF)
Chang, C. W., Mycek, M. A., “Precise fluorophore lifetime mapping in live-cell, multi-photon excitation microscopy”, Optics Express, 2010, 18(8), 8688-8696 (PDF)
Chang, C. W., Wu, M., Merajver, S. D., and Mycek, M. A., “Physiological FLIM improves FRET detection in living cells”, Journal of Biomedical Optics, 2009, 14(6), 060502 (PDF)
Zhong, W., Wu, M., Chang, C. W., Merrick, K. A., Merajver, S. D., Mycek, M. A., “Picosecond-resolution fluorescence lifetime imaging microscopy: a useful tool for sensing molecular interactions in vivo via FRET”, Optics Express, 2007, 15(26),18220-18235 (PDF)
Xu, Z., Raghavan, M., Hall, T. L., Chang, C. W., Mycek, M. A., Fowlkes, J. B., Cain, C. A., “High speed imaging of bubble clouds generated in pulsed ultrasound cavitational therapy-histotripsy”, IEEE Trans. Ultrasonics Ferroelectrics Freq. Control, 2007, 54(10), 2091-2101 (PDF)
Hsu, C. P., Lee, P. H., Chang, C. W., Lee, C. T., “Constructing quantitative models from qualitative mutant phenotypes: preferences in selecting sensory organ precursors”, Bioinformatics, 2006, 22, 1375-1382 (PDF)
Derheimer, F. A., Chang, C. W., Ljungman, M., “Transcription inhibition: a potential strategy for cancer therapeutics”, Eur. J. Cancer, 2005, 41(16), 2569-2576 (PDF)
Chang, C. W., Pi, H., Chien, C. T., Hsu, C.P., “Network modeling of Drosophila external sensory organ precursor formation: the role of recently studied genes”, J. Genet. Mol. Biol., 2003, 14(4), 243-251 (PDF)
Chang, C. W., Kumar, S., “Vinculin tension distributions of individual stress fibers within cell-matrix adhesions”, Journal of Cell Science, 2013, 126(14), 3021-3030 (PDF) (JCS Highlight) (F1000 Review).
Paulsen, M. T., Veloso, A., Prasad, J., Bedi, K., Ljungman, E. A., Tsan, Y. C., Chang, C. W., Tarrier, B., Washburn, J. G., Lyons, R., Robinson, D. R., Kumar-Sinha, C., Wilson, T. E., Ljungman, M., “Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response”, Proceedings of the National Academy of Sciences, 2013, 110(6), 2240-2245 (PDF)
Chang, C. W., Mycek, M. A., “Total variation versus wavelet-based methods for image denoising in fluorescence lifetime imaging microscopy”, Journal of Biophotonics, 2012, 5(5-6), 449-57 (PDF)
Chang, C. W., Mycek, M. A., “Enhancing precision in time-domain fluorescence lifetime imaging”, Journal of Biomedical Optics, 2010, 15(5), 056013 (PDF)
Lloyd, W. R., Wilson, R. H., Chang, C. W., Gillispie, G. D., Mycek, M. A., “Instrumentation to rapidly acquire fluorescence wavelength-time matrices of biological tissues”, Biomedical Optics Express, 2010, 1(2), 574–586 (PDF)
Chang, C. W., Mycek, M. A., “Precise fluorophore lifetime mapping in live-cell, multi-photon excitation microscopy”, Optics Express, 2010, 18(8), 8688-8696 (PDF)
Chang, C. W., Wu, M., Merajver, S. D., and Mycek, M. A., “Physiological FLIM improves FRET detection in living cells”, Journal of Biomedical Optics, 2009, 14(6), 060502 (PDF)
Zhong, W., Wu, M., Chang, C. W., Merrick, K. A., Merajver, S. D., Mycek, M. A., “Picosecond-resolution fluorescence lifetime imaging microscopy: a useful tool for sensing molecular interactions in vivo via FRET”, Optics Express, 2007, 15(26),18220-18235 (PDF)
Xu, Z., Raghavan, M., Hall, T. L., Chang, C. W., Mycek, M. A., Fowlkes, J. B., Cain, C. A., “High speed imaging of bubble clouds generated in pulsed ultrasound cavitational therapy-histotripsy”, IEEE Trans. Ultrasonics Ferroelectrics Freq. Control, 2007, 54(10), 2091-2101 (PDF)
Hsu, C. P., Lee, P. H., Chang, C. W., Lee, C. T., “Constructing quantitative models from qualitative mutant phenotypes: preferences in selecting sensory organ precursors”, Bioinformatics, 2006, 22, 1375-1382 (PDF)
Derheimer, F. A., Chang, C. W., Ljungman, M., “Transcription inhibition: a potential strategy for cancer therapeutics”, Eur. J. Cancer, 2005, 41(16), 2569-2576 (PDF)
Chang, C. W., Pi, H., Chien, C. T., Hsu, C.P., “Network modeling of Drosophila external sensory organ precursor formation: the role of recently studied genes”, J. Genet. Mol. Biol., 2003, 14(4), 243-251 (PDF)
Peer-Reviewed Conference Proceedings
Lloyd, W., Chang, C. W., Wilson, R., Gillispie, G., Mycek, M. A., “Novel clinical technology for rapid detection of tissue fluorescence wavelength-time matrices”, Optical Society of America Biomedical Optics Technical Digest, 2010, JMA96 (3 pages) (PDF)
Chang, C. W. and Mycek, M. A., “Increasing precision of lifetime determination in fluorescence lifetime imaging”, Proceedings of SPIE Photonics West, Biomedical Optics Symposium, 2010, Vol. 7570, 757007 (6 pages) (PDF)
Chang, C. W., Lloyd, W., Wilson, R., Gillispie, G., Mycek, M. A., “Clinically compatible instrumentation for accurate detection of fluorescence intensity and lifetime in turbid media”, Proceedings of SPIE Photonics West, Biomedical Optics Symposium, 2010, Vol. 7555, 755503 (6 pages) (PDF)
Chang, C. W., Wu, M., Merajver, S. D., and Mycek, M. A., “Improving FRET detection in living cells”, Proceedings of SPIE European Conferences on Biomedical Optics, 2009, Vol. 7370, 737007 (7 pages) (PDF)
Chang, C. W. and Mycek, M. A., “Improving precision in time-gated FLIM for low-light live-cell imaging”, Proceedings of SPIE European Conferences on Biomedical Optics, 2009, Vol. 7370, 737009 (6 pages) (PDF)
Chang, C. W. and Mycek, M. A., “Applying image restoration to fluorescence lifetime imaging microscopy (FLIM)”, Proceedings of SPIE European Conferences on Biomedical Optics, 2009, Vol. 7367, 73671E (6 pages) (PDF)
Xu, Z., Raghavan, M., Hall, T. L., Chang, C. W., Mycek, M. A., Fowlkes, J. B., Cain, C. A., “High speed imaging of bubble clouds in pulsed cavitational ultrasound therapy-histotripsy”, Proc. IEEE International Ultrasonics Symposium, 2006, 293 (4 pages) (PDF)
Lloyd, W., Chang, C. W., Wilson, R., Gillispie, G., Mycek, M. A., “Novel clinical technology for rapid detection of tissue fluorescence wavelength-time matrices”, Optical Society of America Biomedical Optics Technical Digest, 2010, JMA96 (3 pages) (PDF)
Chang, C. W. and Mycek, M. A., “Increasing precision of lifetime determination in fluorescence lifetime imaging”, Proceedings of SPIE Photonics West, Biomedical Optics Symposium, 2010, Vol. 7570, 757007 (6 pages) (PDF)
Chang, C. W., Lloyd, W., Wilson, R., Gillispie, G., Mycek, M. A., “Clinically compatible instrumentation for accurate detection of fluorescence intensity and lifetime in turbid media”, Proceedings of SPIE Photonics West, Biomedical Optics Symposium, 2010, Vol. 7555, 755503 (6 pages) (PDF)
Chang, C. W., Wu, M., Merajver, S. D., and Mycek, M. A., “Improving FRET detection in living cells”, Proceedings of SPIE European Conferences on Biomedical Optics, 2009, Vol. 7370, 737007 (7 pages) (PDF)
Chang, C. W. and Mycek, M. A., “Improving precision in time-gated FLIM for low-light live-cell imaging”, Proceedings of SPIE European Conferences on Biomedical Optics, 2009, Vol. 7370, 737009 (6 pages) (PDF)
Chang, C. W. and Mycek, M. A., “Applying image restoration to fluorescence lifetime imaging microscopy (FLIM)”, Proceedings of SPIE European Conferences on Biomedical Optics, 2009, Vol. 7367, 73671E (6 pages) (PDF)
Xu, Z., Raghavan, M., Hall, T. L., Chang, C. W., Mycek, M. A., Fowlkes, J. B., Cain, C. A., “High speed imaging of bubble clouds in pulsed cavitational ultrasound therapy-histotripsy”, Proc. IEEE International Ultrasonics Symposium, 2006, 293 (4 pages) (PDF)
Ph.D. Dissertation
Chang, C. W., "Improving accuracy and precision in biological applications of fluorescence lifetime imaging microscopy" (PDF)
Chang, C. W., "Improving accuracy and precision in biological applications of fluorescence lifetime imaging microscopy" (PDF)